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weekly question 28/12/2025

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A 9-year-old patient with a new diagnosis of de novo pediatric hepatocellular carcinoma is referred to your pediatric surgery clinic. Which of the following features of the tumor would be an indication for evaluation for transplantation?

a Tumor located in segment 4B

b PRETEXT III tumor

c Tumor involving the hilum

d Prior treatment of tumor with TACE
 
correct answer
c Tumor involving the hilum

Pediatric hepatocellular carcinoma tumors should be considered and evaluated for transplantation if they are PRETEXT IV, multifocal in nature, have hilar involvement, and have major vascular involvement including the portal veins, IVC, and hepatic veins. Patients typically undergo liver resection for pediatric hepatocellular carcinoma if they are PRETEXT I, PRETEXT II, and PRETEXT III without high risk features.

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A 9-year-old patient with a new diagnosis of de novo pediatric hepatocellular carcinoma is referred to your pediatric surgery clinic. Which of the following features of the tumor would be an indication for evaluation for transplantation?

a Tumor located in segment 4B

b PRETEXT III tumor

c Tumor involving the hilum

d Prior treatment of tumor with TACE
C
 
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