Quote from "The SAGES Manual of Pediatric Minimally Invasive Surgery" by Danielle S. Walsh, Todd A. Ponsky, Nicholas E. Bruns -
"Catheter occlusions secondary to fibrin or blood clot can be managed with tissue plasminogen activator (TPA). Two milligrams of TPA reconstituted in 40 cc of normal saline, and instilled in the catheter for 1 h, resulted in restoration of patency in 57 % of catheters [26]. Another technique described is the use of an endoscopic retrograde cholangiopancreatography cytology brush to manipulate a malfunctioning PD catheter, with subsequent flushing of the catheter with heparinized saline through the injection port to remove any clot or fibrin."
"Catheter occlusions secondary to fibrin or blood clot can be managed with tissue plasminogen activator (TPA). Two milligrams of TPA reconstituted in 40 cc of normal saline, and instilled in the catheter for 1 h, resulted in restoration of patency in 57 % of catheters [26]. Another technique described is the use of an endoscopic retrograde cholangiopancreatography cytology brush to manipulate a malfunctioning PD catheter, with subsequent flushing of the catheter with heparinized saline through the injection port to remove any clot or fibrin."
Comment