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  • Admin
    Administrator

    • Sep 2020
    • 6950

    #1

    weekly_question 1/6/2025

    You are consulted on a sixteen-year-old who is being evaluated for wheezing unresponsive to bronchodilators. A computerized tomography (CT) scan of the chest is obtained. The most likely diagnosis in this patient with wheezing is

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    a congenital pulmonary airway malformation

    b intralobar pulmonary sequestration.

    c bronchial atresia.

    d extralobar pulmonary sequestration.

    e lobar emphysema.
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  • Answer selected by Admin at 06-03-2025, 04:49 PM.
    Admin
    Administrator

    • Sep 2020
    • 6950

    Correct answer
    c bronchial atresia.

    Bronchial atresia is a congenital abnormality resulting from focal interruption of a lobar, segmental or subsegmental bronchus with associated peripheral mucus impaction, mucocele formation and associated hyperinflation of the distally obstructed lung parenchyma. The diagnosis is suggested on chest radiograph by a perihilar mass with well-defined margins and hyperlucency of the lung parenchyma. High resolution computerized tomography is more sensitive with the following imaging findings: cystic lesion with hypovascularization surrounded by an overinflated pulmonary parenchyma. Three-dimensional rendering defines segmental or lobar involvement.

    The pathogenesis of bronchial atresia is unknown. One theory is that bronchial atresia is caused by an intrauterine ischemic event after the sixteenth week of gestation. The normally developed adjacent parenchyma secretes mucus, with formation of impactions. Ventilation through collateral pores inflates the segment.

    Symptoms include cough, wheezing, dyspnea, recurrent pneumonia, and pneumothorax, although up to half of older patients may be asymptomatic. Most reports recommend surgical resection in symptomatic older children and adults.

    Bronchial atresia is also frequently associated with other congenital lung malformations such as congenital pulmonary airway malformations, extra- and intralobar sequestrations and lobar emphysema suggesting a possible common pathogenesis.

    Comment

    • Ismailmohamed
      Senior Member

      • Dec 2020
      • 106

      #2
      C

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      • Gunduz Aghayev
        Cool Member

        • Sep 2020
        • 77

        #3
        C

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        • M.aldaffaa
          True Member

          • Nov 2020
          • 9

          #4
          C

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          • Anas Fagelnor
            True Member
            • Dec 2024
            • 3

            #5
            C

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            • Dr Lu
              Cool Member

              • Sep 2023
              • 30

              #6
              C

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              • Ismail
                True Member

                • Feb 2022
                • 25

                #7
                C

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                • Admin
                  Administrator

                  • Sep 2020
                  • 6950

                  #8
                  Correct answer
                  c bronchial atresia.

                  Bronchial atresia is a congenital abnormality resulting from focal interruption of a lobar, segmental or subsegmental bronchus with associated peripheral mucus impaction, mucocele formation and associated hyperinflation of the distally obstructed lung parenchyma. The diagnosis is suggested on chest radiograph by a perihilar mass with well-defined margins and hyperlucency of the lung parenchyma. High resolution computerized tomography is more sensitive with the following imaging findings: cystic lesion with hypovascularization surrounded by an overinflated pulmonary parenchyma. Three-dimensional rendering defines segmental or lobar involvement.

                  The pathogenesis of bronchial atresia is unknown. One theory is that bronchial atresia is caused by an intrauterine ischemic event after the sixteenth week of gestation. The normally developed adjacent parenchyma secretes mucus, with formation of impactions. Ventilation through collateral pores inflates the segment.

                  Symptoms include cough, wheezing, dyspnea, recurrent pneumonia, and pneumothorax, although up to half of older patients may be asymptomatic. Most reports recommend surgical resection in symptomatic older children and adults.

                  Bronchial atresia is also frequently associated with other congenital lung malformations such as congenital pulmonary airway malformations, extra- and intralobar sequestrations and lobar emphysema suggesting a possible common pathogenesis.
                  Want to support Pediatric Surgery Club and get Donor status?

                  click here!

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